Search results for "Countercurrent distribution"
showing 4 items of 4 documents
Ionic liquids in separation techniques.
2007
The growing interest in ionic liquids (ILs) has resulted in an exponentially increasing production of analytical applications. The potential of ILs in chemistry is related to their unique properties as non-molecular solvents: a negligible vapor pressure associated to a high thermal stability. ILs found uses in different sub-disciplines of analytical chemistry. After drawing a rapid picture of the physicochemical properties of selected ILs, this review focuses on their use in separation techniques: gas chromatography (GC), liquid chromatography (LC) and electrophoretic methods (CE). In LC and CE, ILs are not used as pure solvents, but rather diluted in aqueous solutions. In this situation IL…
Recent advances on ionic liquid uses in separation techniques
2018
International audience; The molten organic salts with melting point below 100°C, commonly called ionic liquids (ILs) have found numerous uses in separation sciences due to their exceptional properties as non molecular solvents, namely, a negligible vapor pressure, a high thermal stability, and unique solvating properties due to polarity and their ionic character of molten salts. Other properties, such as viscosity, boiling point, water solubility, and electrochemical window, are adjustable playing with which anion is associated with which cation. This review focuses on recent development of the uses of ILs in separation techniques actualizing our 2008 article (same authors, J. Chromatogr. A…
Hydrophobicity of ionisable compounds studied by countercurrent chromatography
2011
Countercurrent chromatography (CCC) is a liquid chromatography technique in which the stationary phase is also a liquid. The main chemical process involved in solute separation is partitioning between the two immiscible liquid phases: the mobile phase and the support-free liquid stationary phase. The octanol-water partition coefficients (P(o/w)) is the accepted parameter measuring the hydrophobicity of molecules. It is considered to estimate active principle partitioning over a biomembrane. It was related to the substance biological activity. CCC is able to work with an octanol stationary phase and an aqueous mobile phase. In this configuration, CCC is a useful and easy alternative to measu…
Countercurrent chromatography: People and applications
2009
The scientific literature was scanned for the published research articles dealing with countercurrent chromatography (CCC) over the time period 1980-May 2008. The search returned 1638 articles that were analyzed focussing on people and applications. Concerning the people, it was found that the geographical location of the CCC authors was relatively well balanced between USA, Asia with mainly China and Japan and Europe. Yoichiro Ito, the inventor of the technique, is by far the most productive author in the field with 331 articles or more than one over five CCC articles published in the time period. Without surprise, English is the dominant language with more than 82% of the articles. A sign…